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Quality systems provide a lot of benefits for customers and all the members of the family of the product’s organization and facilities. Research and Development (R&D) activities are involved in the early stages of the product life cycle. Quality of the product is achieved through the thoroughly applying of the Total Quality Management (TQM) fundamentals on all the value added activities representing the life cycle of the product. This paper indicates the role of TQM to optimize the R&D activities (processes) and suggest the proposed model to attack the problem facing the R&D activities (processes).